Scientific Posters

How Progressive Deconvolution in Byos lifts the dynamic range of intact MS to reveal EPO glycoforms that conventional methods miss.

How automated filtering and Top-3 LFQ make condition-specific isoform biology jump out of complex plasma proteomics data.

How narrower DIA isolation windows plus match-between-runs squeeze more sensitivity out of complex-matrix HCP workflows.

How Byos Oligo automates oligonucleotide impurity analysis across high- and low-resolution LC-MS data with one consistent workflow.

How native CEX-MS, middle-up F(ab')2 strategy, and isotope-envelope-confidence scoring crack the IgG2 disulfide isoform problem.

How scrambling-induced positive controls and automated decision-tree filtering make disulfide characterization tractable in trispecific antibodies.

How automated glycan grouping bridges released-glycan analysis and peptide-level MAM workflows for clean, comparable glycoprofiles.

How combining DIA global profiling with PRM targeted confirmation gives both proteome breadth and high-risk HCP certainty.

How ML- and logic-assisted triage plus traffic-light quality indicators turn complex multispecific MS datasets into rapid clone-ranking decisions.

Which LC-MS workflow finds more impurities — and which one you can actually trust for quantitation?

Byosphere's deep query dashboards unify glycan data, enabling real-time insights, trend analysis, and streamlined therapeutic protein monitoring.

Shift from reactive troubleshooting to proactive monitoring—automated system suitability ensures data confidence and regulatory compliance.

Microtiter plate visualization and traffic light review for multispecific antibodies

Enhancing Discrimination Power in Oligonucleotide Mass Spectrometry Through Internal Fragment Analysis

Achieving Superior Sensitivity and Precision in DIA Protein Quantification

Beyond Conventional Deconvolution: Tackling Complex Biologics and ADCs

Streamline host cell protein discovery with automated quantitation, protein-centric analysis, and interactive dashboards for faster decision-making

Byosphere's deep query dashboards unify glycan data, enabling real-time insights, trend analysis, and streamlined therapeutic protein monitoring.

Advanced ETThcD-MS Workflow for Comprehensive Disulfide Bond Mapping

New Byos search engine improves isoform detection, quantitation precision, and match confidence in complex DIA proteomics workflows.

Map mRNA sequence, cap, and tail in a single LC-MS/MS assay

This poster highlights a protein-centric workflow combining Byos® MPQ with GraphPad Prism to reveal significant trends in complex proteomic datasets.

See how labs across Japan used Byosphere® to analyze MAM data on NISTmAb and uncover differences in sample prep, MS parameters, and CQA quantitation.

This poster presents an MPQ-based workflow for high-throughput CHO proteome analysis, enabling better sensitivity, quantitation, and data inspection.

Streamline host cell protein discovery with automated quantitation, protein-centric analysis, and interactive dashboards for faster decision-making

Map mRNA sequence, cap, and tail in a single LC-MS/MS assay

Orthogonal LC-MS methods simplify lysine-conjugated ADC analysis for precise DAR calculation and site occupancy insights

Streamline host cell protein discovery with automated quantitation, protein-centric analysis, and interactive dashboards for faster decision-making

Progressive deconvolution enables precise detection and quantification of complex biologics across highly heterogeneous samples

Introducing the new multi-protein quantitation mass spectrometric analysis workflow tools for discovery-phase protein scientists.

Byosphere's deep query dashboards unify glycan data, enabling real-time insights, trend analysis, and streamlined therapeutic protein monitoring.

Introducing the new multi-protein quantitation mass spectrometric analysis workflow tools for discovery-phase protein scientists.

An end-to-end automated workflow integrating RapidFire-MS with real-time informatics for high-throughput biologics screening and analysis.

Introducing the new multi-protein quantitation mass spectrometric analysis workflow tools for discovery-phase protein scientists.

A middle-level approach simplifies sample preparation and data analysis for the characterization of the fusion protein Blinatumomab.

Digested oligonucleotide IP-RPLC-MS/MS characterizes mRNA sequence, 5’ cap, and 3’ polyA tail.

Introducing the new multi-protein quantitation mass spectrometric analysis workflow tools for discovery-phase protein scientists.

Charge variant mass spectrometry is used for analyzing biotherapeutics with orthogonal and fractionated sampling.

Released N-linked glycans are annotated and structurally disambiguated through automated spectrum analysis.

Digested oligonucleotide IP-RPLC-MS/MS characterizes mRNA sequence, 5’ cap, and 3’ polyA tail.

A middle-level approach simplifies sample preparation and data analysis for the characterization of the fusion protein Blinatumomab.

A liquid chromatography-tandem mass spectrometry workflow is optimized for mRNA sequence mapping.

Computer modeling evaluates the effectiveness of MS1 and MS2 for mRNA sequence confirmation.

The drug-to-antibody ratio of antibody-drug conjugates is determined in biological samples using microflow-liquid chromatography/HRMS.

Disulfide linkages in the complex cysteine-engineered stapled scFv for bispecific antibodies are optimized and characterized.

Different MS label-free quantitation strategies are assessed for therapeutic proteins.

A middle-level approach simplifies sample preparation and data analysis for the characterization of the fusion protein Blinatumomab.

Charge variant mass spectrometry is used for analyzing biotherapeutics with orthogonal and fractionated sampling.

Integrating tryptic digest peptide data with intact MS data using the new Reconstruction Workflow.

A network method builds a sample-specific glycan database for N-linked glycosylation from MS/MS data.

Improve your organization’s efficiency and capability with automated LCMS analysis of synthetic oligos.

Released N-linked glycans are annotated and structurally disambiguated through automated spectrum analysis.

Released N-linked glycans are annotated and structurally disambiguated through automated spectrum analysis.

A real-time informatics pipeline enables the screening of biologics during high-throughput expression.

A liquid chromatography-tandem mass spectrometry workflow is optimized for mRNA sequence mapping.

Histidine hydrogen-deuterium exchange (His-HDX) mass spectrometry identifies protein-ligand interactions.

Released N-linked glycans are annotated and structurally disambiguated through automated spectrum analysis.

Histidine hydrogen-deuterium exchange (His-HDX) mass spectrometry identifies protein-ligand interactions.

Orthogonal techniques are used for LCMS characterization of a lysine-conjugated ADC.

A novel in vitro serum stability assay for antibody therapeutics incorporates internal standards.

Challenges and strategies are discussed in glycan analysis by MAM.

Glycopeptides are characterized without fragmentation using ion mobility.