Advancements in Multi-Protein Quantitation for Host Cell Protein Discovery

Accelerate host cell protein discovery with automated, multi-protein quantitation and real-time dashboard insights across global biopharma workflows

Multi-Protein Quantitation (MPQ) and HCP Monitoring: Enterprise-Scale Data Intelligence

This technology provides end-to-end quantitative analysis, rapidly supporting discovery, development, and regulatory verification.

  • Rapid, Auto-Curated Analysis:MPQ workflows process gigabytes of input data to produce fast, auto-curated, label-free quantitative analysis for thousands of proteins.
  • Active GxP Monitoring:Utilizes Byosphere® Deep Query Dashboards for active monitoring of Host Cell Protein (HCP) levels across every phase of biopharmaceutical development, from early cell line work to final drug purity verification, within a GxP compliance-ready environment.
  • Automated Quality Control:Byosphere Dashboards are enabled with the ability to set automatic alerts that notify users if proteins of interest fall outside the expected range.
  • Protein-Centric Verification:Provides a protein-centric view and layout that allows analysts to quickly filter, interrogate specific proteins, and gain quicker result verification.
  • Seamless Multi-Lab Alignment:Features like Match Between Runs integrate XICs and align peptide identifications across multiple datasets and differing retention times, crucial for multi-lab studies like the NIST MAM comparisons.

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