Protein Metrics

Version Release Updates

Version 3.6 | September 29th, 2019

Version 3.6 Release Now Available with Powerful New Functionality
Version 3.6 continues to focus on customer success: UI update in Intact, WIFF2 processing, stacked plots, support for in-source dissociation, peak evaluation logic, and more.
  • Read about everything new in the Release Notes. Just go to the Help menu to find this important document – it is 18 pages for this release!
  • Want to enter your protein details much more easily? We have taken your feedback on combining chains, defining the number of disulfide bonds, considering clipped species, setting commonly modified residues, specifying atomic weights, and selecting the biopolymer type (DNA, RNA, and the default protein). Yes, you can now use Byos to analyze oligonucleotides.
  • Want to process WIFF2 files from SCIEX? This is now fully supported.
  • Want to use your own PDB file in 3-D reporting? Now you can.
  • Want to quickly identify in-source dissociation (ISD)? A new column was added to the “Candidates” table in the detached glycan workflows.
  • Want to automatically inspect a degradation or sequence variant project for possible false positives without having to toggle between the project and report? Give the new “Mod Validator” and “SVA Validator” a try.

 


 

Version 3.5 | June 30th, 2019

Version 3.5 Release Now Available with Powerful New Functionality
Version 3.5 continues to focus on customer success: Reporting – 3D visualization, Byos – new columns and report templates, and Beta Releases – Feature Finder and Intact Reconstruction (including tutorials and demo example files).
  • Read about everything new in the Release Notes. Just go to the Help menu to find this important document!
  • Want to show things in more ways? For display and reporting, more tricks have been added, such as Protein 3D Visualization. This new rendering option displays data using the three-dimensional structure of the Protein Data Bank (PDB).
  • Want more ways to automate processing with Byos? New columns make this easier – “Sample Type”, “Sample Number”, and “Replicate”, along with a new report template to support Quantifying Glycation.
  • Want to help us make some new features even better? New Beta releases of Feature Finder and Intact Reconstruction – please give these a try and send us feedback (we even made tutorial guides and prepared demo example files just for you)!
    *Feature Finder – a new algorithm that allows the user to scan the MS1 domain for all existent peptides in a sample.
    *Intact Reconstruction – a way to reconstruct intact mass spectra from peptide mapping data.

 


 

Version 3.4 | March 31st, 2019

Version 3.4 Release Now Available with Powerful New Functionality
Version 3.4 continues the move towards integrating more workflows into the automated Byos® platform. With Hotspot and de novo Sequencing, biopharmaceutical characterization gets deeper and more detailed for those studies. All labs that are working on characterization will benefit from these additions.
  • Scroll bars, peak annotations, peptide scoring for peptidoglycans and ADP-ribose fragments  – all new gadgets that you can read about in the Release Notes. Just go to the Help menu to find the new Quickstart guides and the Release notes. And the updated manuals!
  • Want to show things in more ways? For display and reporting, more tricks have been added, such as R-squared in Line Carts, and the ability to export images in editable formats for Microsoft applications.
  • Pass? Fail? Review? For automated applications – and for example ADC studies – any zero value is now accepted as the reference mass in the traffic light system.
  • Fragmented thinking? Yes, peak annotations for Rapifluor, and low intensity ions.

 


 

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