Research Spotlights
Get the low down on how are tools are being applied in the real world by our customers.
Series Content
- End-to-End Workflow for Bispecific Disulfide Characterization
- Probing Bcl-2 Drug Binding with HDX and Oxidative Footprinting
- Mapping the Sugar Signatures of Immunity and Cancer
- Characterize Bispecific Antibodies
- AI Meets LC-MS: Predicting Antibody Deamidation with Precision
- Comparative Analysis of Herceptin N-Linked Glycosylation
- Comprehensive isoform annotation and quantitation in DIA data
- MS Feature Detection & Quantification
- Oligo QC, Simplified: From Data to Decision in Minutes
- Improving Antibody Stability Screening
- Protein Glycosylation Analysis
- Optimization of a Label-Free Peptide Quantitation Strategy for Analysis of Therapeutic Proteins
End-to-End Workflow for Bispecific Disulfide Characterization
INSIDE THE VIDEO
Johnson & Johnson demonstrates a robust analytical workflow for confirming proper disulfide linkages in stapled bispecific antibodies, with comprehensive data analysis and validation using Protein Metrics software.
LENGTH
3 mins
Comprehensive isoform annotation and quantitation in DIA data
INSIDE THE VIDEO
Our latest poster on DIA proteomics, with a prototype search engine built specifically for data independent acquisition and embedded directly in the Byos.
LENGTH
2 mins
Probing Bcl-2 Drug Binding with HDX and Oxidative Footprinting
INSIDE THE VIDEO
Dual-labeling MS with HDX and OX-MS reveals detailed insights into Bcl-2 binding dynamics with small molecules under identical solution conditions.
LENGTH
3 mins
MS Feature Detection & Quantification
INSIDE THE VIDEO
At PEGS, we unveiled progressive deconvolution: a time-segmented MS approach that resolves complex co-eluting species in glycoproteins and ADCs.
LENGTH
2 mins
Mapping the Sugar Signatures of Immunity and Cancer
INSIDE THE VIDEO
Overlooked glycosylation decoded: released glycan + intact glycopeptide MS profiles neutrophils & tumors, exposing paucimannose—new biomarker leads.
LENGTH
3 mins
Oligo QC, Simplified: From Data to Decision in Minutes
INSIDE THE VIDEO
New oligo resources: explore high-level and step-by-step guides to automate purity and impurity analysis in Byos—fast, clear, and QC-ready.
LENGTH
2 mins
Characterize Bispecific Antibodies
INSIDE THE VIDEO
Explore fast, automated MS workflows in Byos for bispecific antibodies—covering structure, purity, variants, and intact/subunit analysis.
LENGTH
3 mins
Improving Antibody Stability Screening
INSIDE THE VIDEO
See how Byos automates oligo MS workflows—from charge state simplification to purity analysis—for fast, confident QC and regulatory reporting.
LENGTH
2 mins
AI Meets LC-MS: Predicting Antibody Deamidation with Precision
INSIDE THE VIDEO
Combine high-throughput peptide mapping with deep learning to predict antibody deamidation sites accurately—fast, scalable, and automation-ready.
LENGTH
10 mins
Protein Glycosylation Analysis
INSIDE THE VIDEO
Analyze protein glycosylation with Byos—intact, subunit, and glycopeptide data combine for clear insight into structure, occupancy, and variability.
LENGTH
6 mins
Comparative Analysis of Herceptin N-Linked Glycosylation
INSIDE THE VIDEO
Compare N-linked glycosylation on Herceptin lots with Byos to assess structural consistency, detect variants, and ensure product quality.
LENGTH
4 mins
Optimization of a Label-Free Peptide Quantitation Strategy for Analysis of Therapeutic Proteins
INSIDE THE VIDEO
Explore how Byos enables fast, automated quantitation of post-translational modifications (PTMs) across large datasets with accuracy and ease.
LENGTH
6 mins