ASMS 2025 Advancing CHO Proteomics with Multi-Protein Quantitation Workflows
Streamlined, protein-centric LC-MS analysis across fractionation strategies for biopharma development
About this Poster
This poster demonstrates a powerful, protein-centric LC-MS workflow for CHO proteomics using Multi-Protein Quantitation (MPQ) in Byosphere®. The approach compares singleshot and fractionation strategies, showing increased sensitivity and dynamic range using UPS1/2 standards spiked into CHO lysates. Integrated inspection tools, Match Between Runs, and advanced reporting allow for rapid assessment of protein abundance, digestion quality, and analytical variation. Ideal for applications from early discovery to late-stage bioprocessing.
Key Learnings:
- Learn how MPQ workflows support CHO proteomics with scalable, label-free quantitation of complex protein mixtures.
- Discover the benefits of fractionation over singleshot acquisition for deeper proteome coverage.
- See how integrated visualization and inspection features improve QC and method comparison across datasets.
