Automated High-Throughput Screening Using Native MS
Spot the winner in a crowded sky: Automated native MS for rapid hit discovery
Spotting a single functional hit among 280,000 compounds might seem impossible—but with automated native MS workflows, it's becoming routine. Native mass spectrometry (MS) enables ultrafast screening of thousands of small molecules within hours against high value immunology targets. When combined with advanced biochemistry and structural biology workflows in the OMass’ OdyssION™ platform, it accelerates the identification of novel hits within days and enables rapid discovery of potential small-molecule therapeutics for inflammatory diseases.
In this webinar, Kleitos Sokratous will present OMass’ OdyssION™ platform and demonstrate how it was used to screen over 280K compounds against TNFa, leading to the identification and characterization of functional hits within just a few months.
What you will learn
- A high-level overview of OMass’ OdyssION platform™ and how it enables rapid high-throughput screening
- How native MS is applied for true high-throughput small-molecule hit identification
- Approaches for processing native MS data using Byos
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