Evaluation of Multi-Protein Quantitation Workflow for Host Cell Protein Analysis

About this webinar

You never know what you'll find when you look inside—and that's exactly the challenge with host cell protein analysis. This webinar explores the evaluation of a multi-protein quantitation workflow for detecting and performing label-free quantitation of host cell proteins (HCPs). The workflow's performance was compared to the established Host Cell Protein workflow, showing comparable results after initial parameter optimization. Key insights into the workflow's accuracy and quantitation capabilities will be shared, emphasizing its potential as a robust alternative for HCP analysis in biopharmaceutical processes.

Key Takeaways

• Comparison of multi-protein quantitation workflow with the standard HCP workflow revealed comparable performance after parameter optimization
• The workflow provides robust accuracy and quantitation capabilities for HCP detection
• This approach offers a promising alternative for streamlining HCP analysis in early-phase biopharmaceutical development
• Parameter adjustments are critical for achieving optimal results in label-free quantitation workflows

Our Speaker

James York is a Principal Scientist at GlaxoSmithKline (GSK) with expertise in R&D and early-phase development. His day-to-day work includes supporting cell line selection, characterization, and molecule de-risking to advance biopharmaceutical innovation. James brings over 10 years of industrial experience in the development of novel biopharmaceuticals and characterization.