Application Notes & Videos

Byonic Application Notes

Tutorials and Videos


Click HERE to go to Byonic User Manual

Click HERE to go to Byonic FAQ Page

  • Top-down and bottom-up search capabilities
  • Modification Fine Control™ for fast and accurate identification, even with 20+ types of modification
  • Wildcard Search™ for unknown modifications
  • Intact glycopeptide identification
  • Scoring models for all types of fragmentation spectra: CID, TOF-TOF, QTOF HCD, ETD/ECD, and EThcD
  • Sequence variant search and modification site localization


Operates stand-alone or as a node in Thermo Scientific’s Proteome Discover™ versions 1.4, 2.0, and 2.1 releases.

If you would like to install the node in Proteome Discoverer download the appropriate Byonic node.  

See the review from a Thermo Fisher Application Scientist on their Proteomics News Blog.

                Proteomics Search Engine for Discovery Research

Related Products
Byonic™ provides sensitive and comprehensive peptide and protein identification from tandem mass spectrometry data. Byonic™ results can be input into Byologic™ and/or Byomap™ along with the raw mass spec data and any HPLC data.